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Updated: Jul 14, 2025
Use of a Rat Model to Study Ventral Abdominal Hernia Repair
Published on: October 2, 2017
Bubble plastic use in rats hernioplasty: Uso do plástico bolha em hernioplastias de ratos
Siria da Fonseca Jorge1, Carolina Seabra da Costa1, Lycia de Brito Gitirana2
1School of Veterinary Medicine, Center of Health Sciences, Centro Universitário Serra dos Órgãos (UNIFESO) - Estr. Venceslau José de Medeiros, 1045 - Prata, Teresópolis, RJ, 25976-345, Brazil.
Purpose:
Despite the high frequency of hernioplasties worldwide, their complications and recurrences are still a challenge to be overcome. The search for prostheses that aim to promote the correction of hernia defects has been a challenge. For this purpose, the materials used in hernioplasties must be biocompatible, promote the formation of little or no peritoneal adhesion, possess compatible texture and flexibility, providing the necessary resistance to protect the viscera and allow the movement of the abdomen.
Methods:
The aim of the present study was to evaluate the effectiveness of bubble plastic (low density polyethylene, LDPE) as a material for the correction of hernia in the abdominal wall. For this, twenty male rats (Rattus norvegicus, Wistar variety) were used and divided into four groups of five animals. The animals were evaluated at 7, 15, 30 and 90 days after surgery according to clinical, thermographic and morphological parameters (macroscopic and microscopic).
Results:
The results showed that the bubble plastic induced inflammatory reaction in the initial period (7 day), followed by a reduction (30 day) to increase considerably at 90 days after the operation.
Conclusion:
So, bubble plastic can be used for temporary implants (up to 30 days).
