Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

466
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
466
Protein Networks02:26

Protein Networks

4.0K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.0K
Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

2.5K
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
2.5K
Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

812
Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
812
Weighted Mean00:57

Weighted Mean

5.2K
While taking the arithmetic, geometric, or harmonic mean of a sample data set, equal importance is assigned to all the data points. However, all the values may not always be equally important in some data sets. An intrinsic bias might make it more important to give more weightage to specific values over others.
For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
5.2K
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

540
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
540

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of septic joints in the United States: A Nationwide comparison of surgical and non-surgical treatment.

International orthopaedics·2026
Same author

Impact of rheumatoid arthritis on complications and hospital outcomes following reverse shoulder arthroplasty: evidence from 389,135 hospitalizations in the national inpatient sample.

Archives of orthopaedic and trauma surgery·2026
Same author

When the Tibia Hurts: Pain and Revision After Extendable Distal Femoral Endoprostheses in Young Patients.

Indian journal of orthopaedics·2026
Same author

Perioperative Outcomes of Cemented vs Cementless Total Hip Arthroplasty: A National Inpatient Sample Study of 81,668 Elective Procedures.

Journal of clinical medicine·2026
Same author

Influence of Arthroplasty Type, Comorbidities, and Fracture Status on Outcomes After Shoulder Replacement: Analysis of 664,545 Cases.

Healthcare (Basel, Switzerland)·2026
Same author

A generalized SEIRW-VN framework for modeling infectious disease dynamics.

Scientific reports·2026
Same journal

Correction: A method for supervoxel-wise association studies of age and other non-imaging variables from coronary computed tomography angiograms.

Scientific reports·2026
Same journal

Poly(bromophenol blue)/CoSn(OH)<sub>6</sub> cubic particles modified pencil graphite electrode for electrochemical determination of diphenhydramine.

Scientific reports·2026
Same journal

Dietary Chlorella, Spirulina, and acidifier modulate jejunal cytokine-related gene expression in broiler chickens.

Scientific reports·2026
Same journal

Perceived physical activity barriers in university students: associations with fatigue and eating behaviours.

Scientific reports·2026
Same journal

Refuge limitation structures habitat use in agricultural landscapes: evidence from Sunda pangolins.

Scientific reports·2026
Same journal

Lightweight stateless transaction verification with outsourced witness updates for UTXO blockchains.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Jul 14, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K

An evaluation tool for backbone extraction techniques in weighted complex networks.

Ali Yassin1, Abbas Haidar2, Hocine Cherifi3

  • 1Laboratoire d'Informatique de Bourgogne, University of Burgundy, Dijon, France. ali_yassin@etu.u-bourgogne.fr.

Scientific Reports
|October 9, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces netbone, a Python package for evaluating backbone extraction techniques in complex networks. It offers a framework to compare methods and metrics, aiding researchers in selecting optimal techniques for network analysis.

More Related Videos

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.4K
Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.7K

Related Experiment Videos

Last Updated: Jul 14, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K
Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.4K
Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.7K

Area of Science:

  • Network Science
  • Computational Science

Background:

  • Analyzing large, complex systems often requires network analysis.
  • Extracting network backbones is crucial for reducing complexity while preserving essential features.
  • Evaluating and comparing different backbone extraction methods can be challenging.

Purpose of the Study:

  • To introduce netbone, a Python package for assessing backbone extraction technique performance in weighted networks.
  • To provide a standardized framework for comparing state-of-the-art backbone extraction methods.
  • To facilitate informed decision-making for researchers and practitioners in network analysis.

Main Methods:

  • Development of the netbone Python package.
  • Incorporation of state-of-the-art backbone extraction techniques.
  • Implementation of a comprehensive suite of evaluation metrics for performance assessment.
  • Application to the US air transportation network for illustrative analysis.

Main Results:

  • netbone provides a flexible and effective comparison framework for backbone extraction techniques.
  • The tool allows for the evaluation of different techniques using standardized metrics.
  • Users can integrate new backbone extraction methods into the existing framework.
  • Analysis of the US air transportation network demonstrates netbone's utility.

Conclusions:

  • netbone is a valuable open-source resource for researchers and practitioners in network science.
  • The package promotes standardized evaluation practices, enhancing reproducibility and comparability.
  • netbone enables informed selection of backbone extraction techniques for network analysis.
  • The tool aids in gaining deeper insights into the structural and functional properties of complex systems.