Related Experiment Video
Updated: Jul 13, 2025
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Lanolin: The 2023 American Contact Dermatitis Society Allergen of the Year
Hadley Johnson1, Thomas Norman1, Brandon L Adler1
1Hadley Johnson is from the University of Minnesota Medical School, Minneapolis. Thomas Norman and Dr. Adler are from the Keck School of Medicine, University of Southern California, Los Angeles. Dr. Adler is from the Department of Dermatology. Dr. Yu is from the Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston.
Abstract:
In 2023, lanolin was named the American Contact Dermatitis Society Allergen of the Year. Despite its widespread use in personal care products and industrial goods, lanolin is thought to be a rare sensitizer in patients with healthy skin; however, those with chronic inflammatory skin conditions are at a higher risk for allergic contact dermatitis (ACD) to lanolin. The proper patch test formulation for lanolin is a source of contention. In this article, we discuss ACD to lanolin with a focus on its paradoxical nature and the subtleties to consider when patch testing to this controversial allergen.
Related Concept Videos
02:06Allergic Reactions
01:27Allergic Drug Reactions
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...