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Aging Skin and Natural Bioactives that Impede Cutaneous Aging: A Narrative Review
1From the Department of Pharmacognosy, College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences, (A Govt of Puducherry Institution), Gorimedu, Puducherry, India.
Indian Journal of Dermatology
|October 12, 2023
Summary
This review explores natural bioactives for anti-aging skin care, highlighting their antioxidant and protective properties. It also examines AI
Area of Science:
- Dermatology and cosmetic science.
- Pharmacology and natural product research.
- Bioinformatics and artificial intelligence in drug discovery.
Background:
- Skin aging is a complex process influenced by intrinsic and extrinsic factors.
- Conventional anti-aging products often contain chemical constituents with potential adverse health and environmental effects.
- There is a growing demand for natural, safe, and effective anti-aging solutions.
Purpose of the Study:
- To critically review the impact of aging determinants on skin.
- To identify and evaluate natural bioactive compounds that counteract skin aging symptoms.
- To explore the role of artificial learning in screening and formulating these bioactives.
Main Methods:
- A narrative review of scientific literature from databases like PubMed and Scopus.
- Inclusion of findings from hand searches and authoritative books.
- Discussion of artificial learning/machine-based algorithms for bioactive screening.
Main Results:
- Natural bioactives function as antioxidants, moisturizers, and UV protectants, offering potential anti-aging benefits.
- These compounds are increasingly favored over synthetic alternatives due to safety concerns.
- AI algorithms show promise in identifying and developing tailored bioactive formulations.
Conclusions:
- Natural bioactives represent a promising avenue for developing effective and safe anti-aging skincare.
- Integrating artificial intelligence can accelerate the discovery and application of these compounds.
- The focus of aesthetic dermatology should evolve towards promoting overall quality of life through healthy aging.
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