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Characterization of Austrian severe asthma patients
Andreas Renner1, Slagjana Stoshikj1, Wolfgang Pohl2
1Department of Pneumology, University Hospital Vienna, Medical University of Vienna, Vienna, Austria.
Respiratory Medicine
|October 12, 2023
Summary
The Severe Asthma Registry in Austria characterized 214 severe asthma patients, finding better control and fewer exacerbations than international cohorts. This provides crucial insights into severe asthma management in the region.
Area of Science:
- Pulmonology
- Clinical Research
- Epidemiology
Background:
- The German Asthma Net (GAN) established the Severe Asthma Registry in 2011.
- This registry prospectively collects clinical data from severe asthma patients across Germany, Austria, and Switzerland.
- This study focuses on the baseline characteristics of severe asthma patients from Austrian centers within the GAN registry.
Purpose of the Study:
- To present the baseline characteristics of severe asthma patients from Austrian centers participating in the GAN Severe Asthma Registry.
- To provide a multi-center characterization of this specific patient cohort.
Main Methods:
- Analysis of baseline visit data from 214 severe asthma patients recruited from 6 Austrian centers (2013-2022).
- Data included demographics, symptom frequency, asthma control (GINA criteria), exacerbation rates, and current treatments (oral corticosteroids, monoclonal antibodies).
Main Results:
- The cohort (n=214) had a mean age of 53.7 years and a mean BMI of 26.4 kg/m².
- Over a third experienced daily symptoms and reliever use; 41% were uncontrolled (GINA).
- Median annual exacerbations were 3; 23.4% used oral corticosteroids, and 23.9% had prior monoclonal antibody treatment.
Conclusions:
- This study offers the first multi-center characterization of Austrian severe asthma patients.
- Compared to international registries, patients in this Austrian cohort demonstrated better asthma control and experienced less frequent exacerbations.
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