Related Experiment Video
Updated: Jul 13, 2025
07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
6.4K
Improving the Accuracy and Speed of Visual Field Testing in Glaucoma With Structural Information and Deep Learning
Giovanni Montesano1,2, Georgios Lazaridis1,2,3, Giovanni Ometto1,2
1City, University of London, Optometry and Visual Sciences, London, UK.
Translational Vision Science & Technology
|October 13, 2023
Summary
Deep learning (DL) models improve glaucoma perimetry by using structure-function predictions from OCT scans. This enhanced approach significantly speeds up visual field testing and increases accuracy.
Area of Science:
- Ophthalmology
- Medical Imaging
- Artificial Intelligence
Background:
- Glaucoma diagnosis and monitoring rely on visual field testing.
- Perimetric strategies aim to efficiently and accurately assess visual field sensitivity.
- Deep learning (DL) models offer potential for improving diagnostic tools.
Purpose of the Study:
- To evaluate a perimetric strategy enhanced by structure-function predictions from a DL model.
- To compare the speed and accuracy of DL-informed perimetry against traditional methods.
Main Methods:
- Utilized visual field test-retest data from 146 glaucoma patient eyes.
- Generated structure-function predictions using a DL model with OCT scans.
- Compared a standard Zippy Estimation by Sequential Testing (ZEST) strategy with a structure-informed ZEST (S-ZEST) strategy.
Main Results:
- S-ZEST demonstrated significantly higher speed (fewer presentations) and accuracy (lower mean absolute error) compared to ZEST.
- The inclusion of spatial correlations further enhanced both strategies.
- DL-based structure-function predictions notably improved perimetric test performance.
Conclusions:
- DL structure-function predictions derived from OCT scans significantly enhance perimetric tests in glaucoma patients.
- This advancement offers a more efficient and accurate method for visual field assessment.
More Related Videos
Related Concept Videos
01:25Glaucoma: Overview
600
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
600
01:27Open Angle Glaucoma: Treatment
471
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
471
01:28Angle Closure Glaucoma: Treatment
540
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
540