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Updated: Jul 13, 2025

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
Published on: February 16, 2018
Fast, selective, and sensitive detection of 2,4-dichlorophenol by an imprinted polymer functionalized core-offset
Abstract:
Pollution monitoring in waterways and oceans is often performed in a laboratory on samples previously taken from the environment. The integration of molecular imprinting polymer nanoparticles (MIP-NPs) with a novel, to the best of our knowledge, fiber optic interferometer allowed a fast and selective detection of water pollutant 2,4-Dichlorophenol (2,4-DCP). The proposed sensor with an increased surface-to-volume ratio of MIP-NPs provided an enhanced sensitivity of 17.1 nm/µM and a wide operating range of 0.1-100 µM. It showed a highly repeatable performance and potential to measure up to nM concentrations. This integrated technique is suitable for the development of compact, stable, precise, and sensitive biosensors for online monitoring and remote chemical sensing applications.
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