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Adhesion-based capture stabilizes nascent microvilli at epithelial cell junctions

Caroline S Cencer1, Jennifer B Silverman1, Leslie M Meenderink2

  • 1Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Developmental Cell
|October 13, 2023
PubMed
Summary

Epithelial cells form a brush border using intermicrovillar adhesion complexes (IMACs) to stabilize new microvilli at cell junctions. This marginal capture mechanism is crucial for developing mature apical specializations.

Keywords:
actinbrush bordercadherinsdifferentiationintermicrovillar adhesiontransporting epithelia

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