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Updated: Jul 13, 2025

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
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Selenium Injection in Dam Rabbits During Gestation Has Important Effects on Progeny Productive Performance.

Alejandra García-Medina1, Luis Becerril-Martínez1, G Manuel Parra-Bracamonte2

  • 1Centro Genético Porcino "La Concepción", 50830, Jiquipilco, México, Mexico.

Biological Trace Element Research
|October 13, 2023
PubMed
Summary
This summary is machine-generated.

Selenium injections during rabbit pregnancy improved progeny development, affecting carcass traits and organ weights. Gestational selenium supplementation positively influenced offspring growth and metabolic profiles.

Keywords:
Fetal growthOrganogenesisProductive performanceSelenium

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Area of Science:

  • Animal Science
  • Reproductive Biology
  • Nutritional Science

Background:

  • Micromineral elements are crucial for organogenesis and fetal development.
  • Selenium (Se) plays a vital role in mammalian reproduction and embryonic development.

Purpose of the Study:

  • To evaluate the impact of selenium (Se) injection in pregnant rabbits during critical developmental stages on their offspring's productive performance.
  • To determine if the timing of Se administration (organogenesis vs. rapid fetal growth) influences progeny outcomes.

Main Methods:

  • 30 pregnant New Zealand rabbits were divided into three groups: Control (saline), Early Se administration (day 13), and Late Se administration (day 23).
  • Selenium was administered intramuscularly at 0.10 mg/kg body weight during specific gestation periods.
  • Offspring were assessed for kindling performance, pre-weaning growth, carcass traits, organ weights, and blood biochemical parameters.

Main Results:

  • No significant differences were observed in dam kindling performance or offspring pre-weaning growth.
  • Selenium administration altered progeny carcass traits (forelimb weight/muscle) and organ weights (liver, lungs, spleen).
  • Se-treated groups exhibited lower glucose, triglyceride, and cholesterol levels compared to controls, with timing-dependent effects.

Conclusions:

  • Gestational selenium injection in rabbits positively impacts offspring carcass and organ development.
  • The timing of selenium administration during gestation influences specific developmental and metabolic outcomes in progeny.
  • Selenium supplementation during pregnancy offers potential benefits for rabbit production traits.