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A Protocol to Acquire the Degenerative Tenocyte from Humans
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Regenerative Therapies for Basal Thumb Arthritis-A Systematic Review.

Sophie Hasiba-Pappas1, Lars-P Kamolz1,2, Hanna Luze1

  • 1Research Unit for Tissue Regeneration, Repair and Reconstruction, Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Auenbruggerplatz 5, A-8036 Graz, Austria.

International Journal of Molecular Sciences
|October 14, 2023
PubMed
Summary

Novel regenerative therapies like platelet-rich plasma (PRP) and fat grafting show promise for basal thumb arthritis, offering potential pain relief and improved function. More research is needed to confirm long-term benefits and cartilage repair capabilities.

Keywords:
LLLTcarpometacarpal arthritischondrocyte transplantfat graftinglipofillingphototherapyplatelet-rich plasmaregenerative therapyrhizarthrosis

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Area of Science:

  • Orthopedics
  • Regenerative Medicine
  • Hand Surgery

Background:

  • Basal thumb arthritis significantly impacts quality of life.
  • Current treatments (pain control, steroids, surgery) lack long-term efficacy data and cartilage repair evidence.
  • Novel regenerative approaches are emerging for this condition.

Conclusions:

  • Platelet-rich plasma (PRP) and lipofilling (fat grafting) demonstrate promising results for basal thumb arthritis.
  • These regenerative therapies warrant further investigation for efficacy and cartilage repair potential.
  • More robust clinical trials are needed to establish long-term benefits.