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Celochalcoside, a new quinochalcone C-glycoside from Celosia trigyna
1Chemistry Department, Faculty of Science, Jazan University, Jazan 2097, Kingdom of Saudi Arabia.
Journal of Asian Natural Products Research
|October 16, 2023
Abstract:
A new quinochalcone C-glycoside featuring a unique quinonoid moiety, named celochalcoside (1), was isolated from the n-butanol extract of the aerial parts of Celosia trigyna L. The structure was determined by extensive spectroscopic analysis as well as mass spectrometric data. Compound 1 showed moderate cytotoxic activities against breast cancer cell lines (MCF-7), colon cancer cell lines (HT-29) and hepatocellular carcinoma cell lines (HepG2) with IC50 values of 23.16, 37.05 and 18.35 μg/ml, respectively.

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