Related Experiment Video
Updated: Jul 13, 2025

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
Bisphospholane Josiphos-type Ligands in Rhodium Asymmetric Catalysis
1Department of Safety Supervision and Management, Chongqing Vocational Institute of Safety Technology, 583 Anqing road, Wanzhou district, Chongqing, 404020, China.
Abstract:
Asymmetric catalysis has become a universal and powerful method for constructing chiral compounds. In rhodium asymmetric catalysis, bisphospholane Josiphos-type ligands and their rhodium complexes are receiving increasing attention. This review provides comprehensive information on the bisphospholane Josiphos-type ligands in rhodium asymmetric catalysis. The scope of the literature covers from 2013 to now. The application of bisphospholane Josiphos-type ligands in rhodium asymmetric catalysis is summarized as follows: (i) asymmetric addition to C(sp2 )-C(sp2 ) bonds, (ii) asymmetric addition to C(sp2 )-C(sp) bonds of allenes, (iii) asymmetric hydrogenation of C(sp2 )-N bonds, C(sp2 )-O bonds and pyridinium salts, and (iv) asymmetric silanization of C-H and O-H bonds.
More Related Videos
10:52Line Shape Analysis of Dynamic NMR Spectra for Characterizing Coordination Sphere Rearrangements at a Chiral Rhenium Polyhydride Complex
Published on: July 27, 2022
08:46Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of PhosphorusI
Published on: November 22, 2016
Related Concept Videos
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Aldehydes and Ketones to Alkenes: Wittig Reaction Overview
Aldehydes and Ketones to Alkenes: Wittig Reaction Mechanism
The reaction begins with the nucleophilic addition between a phosphorus ylide and the carbonyl compound. Due to its carbanionic character, phosphorus ylide acts as a strong nucleophile and attacks the electrophilic carbonyl group. This generates a charge-separated dipolar intermediate called betaine. The negatively charged oxygen atom and...
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Regioselectivity and Stereochemistry of Hydroboration
Hydroboration proceeds in a concerted fashion with the attack of borane on the π bond, giving a cyclic four-centered transition state. The –BH2 group is bonded to the less substituted carbon and –H to the more substituted carbon. The concerted nature requires the simultaneous addition of –H and –BH2 across the same face of the alkene giving syn...
Preparation and Reactions of Sulfides