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Assaying for Inorganic Polyphosphate in Bacteria
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Assaying for Inorganic Polyphosphate in Bacteria

Published on: January 21, 2019

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Evolutionary perspective on mammalian inorganic polyphosphate (polyP) biology

Filipy Borghi1, Adolfo Saiardi1

  • 1Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, U.K.

Biochemical Society Transactions
|October 16, 2023
PubMed
Summary

Inorganic polyphosphate (polyP) likely existed in ancestral eukaryotes but was lost in most lineages. Eukaryotic cells evolved mechanisms to control polyP levels, with potential roles in mitochondria and the nucleus.

Keywords:
evolutioninorganic polyphosphateinositol pyrophosphatemetabolismmitochondrianucleus

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