Related Experiment Video
Updated: Jul 13, 2025
12:23
Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
14.1K
Evidence-based management of optic neuritis.
Emilie Bergeron1,2, Marc A Bouffard1
1Division of Neuro-Ophthalmology, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.
Current Opinion in Ophthalmology
|October 17, 2023
Summary
Prompt treatment for optic neuritis, including intravenous methylprednisolone (IVMP) and plasmapheresis for neuromyelitis optica spectrum disorder (NMOSD), improves visual recovery. Long-term immunosuppression is recommended for NMOSD and MOGAD.
Area of Science:
- Neuro-immunology
- Ophthalmology
- Neurology
Background:
- Optic neuritis presents with diverse etiologies, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody disease (MOGAD).
- Differentiating these causes is crucial for effective therapeutic strategies.
Conclusions:
- IVMP is a standard treatment for acute optic neuritis.
- Plasmapheresis is a critical adjunct for NMOSD-associated optic neuritis.
- Long-term immunosuppressive therapy is indicated for NMOSD and MOGAD patients experiencing poor visual outcomes or recurrent attacks.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
459
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
459
01:28Angle Closure Glaucoma: Treatment
536
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
536
01:25Glaucoma: Overview
599
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
599