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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
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Cancer and Atrial Fibrillation Comorbidities Among 25 Million Citizens in Shanghai, China: Medical Insurance Database
Mu Chen1, Cheng Li1, Jiwei Zhang2
1Department of Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
JMIR Public Health and Surveillance
|October 17, 2023
Summary
Atrial fibrillation (AF) is linked to a higher prevalence of cancer, particularly in men and at younger ages. This study highlights the need for further research into early cancer screening for AF patients.
Area of Science:
- Epidemiology
- Oncology
- Cardiology
Background:
- Rising global prevalence of cancer and atrial fibrillation (AF) due to population aging.
- Limited epidemiological data on the co-occurrence of cancer and AF in low- and middle-income countries like China.
Purpose of the Study:
- To investigate the site-, sex-, and age-specific characteristics of cancer and AF comorbidities in Chinese populations.
- To assess cancer prevalence in individuals with AF compared to those without.
Main Methods:
- Screening of medical records from Shanghai residents (2015-2020).
- Comparative analysis of cancer profiles between AF patients and age/sex-adjusted non-AF residents.
- Evaluation of sex distribution and peak age of cancer diagnosis.
Main Results:
- Higher cancer prevalence (8.27%) observed in patients with AF versus those without (6.05%).
- AF associated with a 1.37-fold increased cancer prevalence, most notably for nonsolid tumors, intrathoracic malignancies, and kidney cancer.
- Cancer diagnosis in AF patients occurred at a younger peak age and showed male predominance across most cancer sites.
Conclusions:
- Atrial fibrillation is associated with increased cancer prevalence, male predominance, and earlier diagnosis.
- Further research is warranted to explore the cost-effectiveness and benefits of early cancer screening in AF patient populations.
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