[Radiotherapy of esophageal cancer using local hyperthermia and metronidazole (polyradiomodification)]

The results of a dynamic course of radiotherapy alone and in combination with local hyperthermia and metronidazole were studied in 107 patients with esophageal cancer. With relation to the methods applied the patients were divided into 4 groups: the 1st group (40 patients) was given radiotherapy, the 2nd group (24 patients) radiotherapy and metronidazole, the 3rd group (20 patients) radiotherapy and local hyperthermia, and the 4th group (18 patients) radiotherapy, metronidazole and local hyperthermia. The general direct therapeutic efficacy and 1-year survival for the 1st group were 75 and 76.7% respectively, for the 2nd group 79.3 and 86.9%, for the 3rd group 100 and 95%, and for the 4th group 100 and 94.4%. Thus, a high efficacy of polyradiomodification in esophageal cancer was established.