Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Correlations02:20

Correlations

32.8K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
32.8K
Correlation of Experimental Data01:23

Correlation of Experimental Data

235
Dimensional analysis simplifies complex physical problems and guides experimental investigations, but it does not provide complete solutions. It identifies the dimensionless groups that influence a phenomenon, but experimental data is needed to establish the specific relationships and validate theoretical predictions.
For example, a spherical particle moving through a viscous fluid experiences drag. Dimensional analysis shows that the drag force depends on the particle's diameter, velocity,...
235
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

34.4K
VSEPR Theory for Determination of Electron Pair Geometries
34.4K
Calculating and Interpreting the Linear Correlation Coefficient01:11

Calculating and Interpreting the Linear Correlation Coefficient

6.0K
The correlation coefficient, r, developed by Karl Pearson in the early 1900s, is numerical and provides a measure of strength and direction of the linear association between the independent variable, x, and the dependent variable, y. Hence, it is also known as the Pearson product-moment correlation coefficient. It can be calculated using the following equation:
6.0K
VSEPR Theory and the Effect of Lone Pairs04:01

VSEPR Theory and the Effect of Lone Pairs

42.4K
Effect of Lone Pairs of Electrons on Molecule Geometry
42.4K
2D NMR: Overview of Homonuclear Correlation Techniques01:16

2D NMR: Overview of Homonuclear Correlation Techniques

211
Homonuclear correlation spectroscopy (COSY) is a powerful technique used in Nuclear Magnetic Resonance (NMR) spectroscopy to study the correlations between nuclei of the same type within a molecule. It provides information about scalar couplings between adjacent nuclei, which helps determine connectivity and structural information. There are several COSY variants, each with its unique strengths and experimental parameters.
COSY90 is the standard two-dimensional (2D) COSY experiment that...
211

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Random-with-constraints: Constructing minimal models for high-dimensional biology.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

The hierarchical timescale hypothesis: Functional and structural convergence of biological networks and artificial neural nets.

Cell systems·2026
Same author

Distribution of singular values in large sample cross-covariance matrices.

Physical review. E·2025
Same author

Randomness with constraints: constructing minimal models for high-dimensional biology.

ArXiv·2025
Same author

Physics-tailored machine learning reveals unexpected physics in dusty plasmas.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

A mathematical model for ketosis-prone diabetes suggests the existence of multiple pancreatic β-cell inactivation mechanisms.

eLife·2025

Related Experiment Video

Updated: Jul 13, 2025

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

15.5K

Inferring local structure from pairwise correlations.

Mahajabin Rahman1, Ilya Nemenman2

  • 1Department of Physics, Emory University, Atlanta, Georgia 30322, USA.

Physical Review. E
|October 18, 2023
PubMed
Summary

Pairwise correlations in complex systems, even with limited data, can reveal local structures and data dimensionality. This method aids in reconstructing scrambled data and understanding machine learning models.

More Related Videos

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
14:55

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

15.5K
Super-Resolution Imaging to Study Co-Localization of Proteins and Synaptic Markers in Primary Neurons
14:02

Super-Resolution Imaging to Study Co-Localization of Proteins and Synaptic Markers in Primary Neurons

Published on: October 31, 2020

5.8K

Related Experiment Videos

Last Updated: Jul 13, 2025

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

15.5K
Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
14:55

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

15.5K
Super-Resolution Imaging to Study Co-Localization of Proteins and Synaptic Markers in Primary Neurons
14:02

Super-Resolution Imaging to Study Co-Localization of Proteins and Synaptic Markers in Primary Neurons

Published on: October 31, 2020

5.8K

Area of Science:

  • Complex Systems Modeling
  • Machine Learning Theory
  • Data Analysis

Background:

  • Modeling complex systems requires identifying variable interactions.
  • Detecting local structures is crucial for understanding multivariate systems.
  • Modern machine learning, like attention mechanisms, shows promise in handling complexity.

Purpose of the Study:

  • To investigate if pairwise correlations can recover local structures in complex systems.
  • To determine if this approach is effective even with undersampled and noisy data.
  • To provide insights into the success of modern machine learning techniques.

Main Methods:

  • Utilized a toy model of 2D natural and synthetic images.
  • Analyzed pairwise correlations between variables under severe undersampling.
  • Assessed the ability to recover local relations and data dimensionality.

Main Results:

  • Pairwise correlations successfully recovered local relations and data dimensionality.
  • Reconstruction of pixel arrangements in scrambled images was achieved.
  • Effectiveness was demonstrated despite the presence of higher-order interactions.

Conclusions:

  • Pairwise correlations are sufficient for inferring local structures in complex systems.
  • This approach offers a method for modeling complex systems and explaining machine learning successes.
  • The findings have implications for both theoretical modeling and practical applications in AI.