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Left Ventricular Noncompaction in Concomitance With Heroin Use Disorder.

Yashitha Chirumamilla1, Nihara Chakrala1, Huda Marcus2

  • 1Internal Medicine, Hurley Medical Center, Flint, USA.

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|October 18, 2023
PubMed
Summary
This summary is machine-generated.

Left ventricular noncompaction (LVNC) is a rare heart condition. This case highlights LVNC diagnosis in a patient presenting with syncope after substance use, emphasizing the need for cardiac evaluation in such scenarios.

Keywords:
congenital cardiomyopathyheroin useheroin use disorderleft ventricular noncompactionleft ventricular noncompaction cardiomyopathy

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Area of Science:

  • Cardiology
  • Genetics

Background:

  • Left ventricular noncompaction (LVNC) is a rare congenital cardiomyopathy.
  • It is characterized by prominent myocardial trabeculations and deep intertrabecular recesses.
  • Clinical manifestations range from asymptomatic to heart failure, arrhythmias, and thromboembolism.

Observation:

  • A 42-year-old female with a history of asthma and substance use disorder presented with syncope after intranasal heroin use.
  • Initial evaluation revealed aspiration pneumonia; however, persistent chest pain prompted further cardiac assessment.
  • Electrocardiography showed normal sinus rhythm without acute ischemic changes.

Findings:

  • Echocardiography revealed left ventricular apical trabeculations, consistent with LVNC.
  • The patient exhibited normal systolic and diastolic function.
  • The syncopal event was attributed to potential underlying arrhythmias, exacerbated by substance use.

Implications:

  • This case underscores the importance of considering cardiac causes, including LVNC, in patients presenting with syncope, especially those with a history of substance use.
  • Close cardiac follow-up, including monitoring for arrhythmias, is crucial for patients diagnosed with LVNC and engaging in high-risk behaviors.
  • Abstinence from substance use is strongly advised to mitigate cardiac risks.