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Plant Biosystems Design Research Roadmap 1.0.

Xiaohan Yang1,2, June I Medford3, Kasey Markel4

  • 1Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.

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|October 18, 2023
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Summary
This summary is machine-generated.

Plant biosystems design offers innovative strategies to improve crop yield and quality, addressing global needs. This approach uses predictive models and advanced techniques like genome editing for accelerated plant genetic improvement and novel system creation.

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Area of Science:

  • Plant Science
  • Synthetic Biology
  • Bioengineering

Background:

  • Human survival and well-being are fundamentally reliant on plants for essential resources like food, materials, and energy.
  • Current genetic improvement methods for plants, including breeding and limited genetic engineering, are insufficient to meet escalating global demands for quantity and quality.

Purpose of the Study:

  • To present a comprehensive roadmap for plant biosystems design, outlining theories, principles, and methods.
  • To explore the potential applications of plant biosystems design in both fundamental and applied plant biology.
  • To identify challenges, opportunities, and priorities for advancing this interdisciplinary field.

Main Methods:

  • Utilizing predictive models of biological systems for innovative plant science research.
  • Employing genome editing and genetic circuit engineering for accelerated plant genetic improvement.
  • Exploring de novo synthesis of plant genomes for creating novel plant systems.

Main Results:

  • Plant biosystems design represents a paradigm shift from trial-and-error to predictive, model-based strategies.
  • This approach facilitates rapid genetic improvement and the creation of entirely new plant functionalities.
  • A roadmap is provided, detailing theoretical frameworks, technical methodologies, and application potentials.

Conclusions:

  • Plant biosystems design is crucial for addressing global challenges in food security and sustainability.
  • International collaboration and a focus on social responsibility are vital for public acceptance and the advancement of this field.
  • Future research should prioritize developing robust biosystems design frameworks and fostering public trust.