Related Experiment Video

Updated: Jul 6, 2026

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

13.0K

Impact of multiple sclerosis risk alleles on the plasma proteome

Shannon A Bernard Healey1, Gavin Giovannoni1,2, Alastair Noyce1,2

  • 1Centre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University of London, London, EC1M 6BQ, UK.

Brain : a Journal of Neurology
|October 18, 2023
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

7.9K
Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

869

Related Experiment Videos

Last Updated: Jul 6, 2026

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

13.0K
A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

7.9K
Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

869

Related Concept Videos

Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu01:29

Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu

Genetic variations significantly influence drug response through pharmacokinetics, receptor interactions, and biologic milieu modifications. Pharmacokinetic alterations impact drug metabolism and clearance, affecting efficacy and toxicity. Variants in drug-metabolizing enzymes, such as CYP2C9 and CYP2C19, alter drug activation and elimination. For example, CYP2C9 loss-of-function variants require lower warfarin doses to prevent excessive bleeding, while CYP2C19 variants reduce clopidogrel...
Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

Articles linked to this work by shared authors, journal, and citation graph.

Environmental determinants of Parkinson's disease and attributable burden in Latin America.

Research square·2026

Mapping the Parkinson's pandemic: Unveiling and addressing the global burden.

Journal of Parkinson's disease·2026

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study.

Annals of clinical and translational neurology·2026

An ancestry-enriched HNF4A variant and GP2 reveal distinct mechanisms of type 2 diabetes in exome-wide study of 13,674 cases and 41,024 controls.

medRxiv : the preprint server for health sciences·2026

The contribution of apolipoprotein E genetic variation to dementia risk in British South Asians.

Brain communications·2026

No evidence for a causal link between plasma lipids and multiple sclerosis susceptibility and severity: A Mendelian randomisation study.

Journal of the neurological sciences·2026

Tyrosyl-tRNA sequestration triggers tyrosyl-tRNA synthetase-associated peripheral neuropathy.

Brain : a journal of neurology·2026

Progress towards a biotypic biomarker profile for amyotrophic lateral sclerosis-frontotemporal spectrum disorders.

Brain : a journal of neurology·2026

AGG repeat expansion and aggregation of BIN1 in multiple system atrophy.

Brain : a journal of neurology·2026

Diagnosing multiple sclerosis: implementation and unintended effects of the 2024 McDonald criteria.

Brain : a journal of neurology·2026

Viral mimetic triggers haemorrhagic transformation in a childhood stroke model via neutrophil elastase.

Brain : a journal of neurology·2026

De novo chromatin remodelling variants in sporadic Chiari 1 malformation.

Brain : a journal of neurology·2026

Preservation of Nociceptor Intraepidermal Nerve Fibres in Diabetic Neuropathic Pain.

Journal of diabetes research·2026

Preoperative CT-Guided Cryoneurolysis of the Genicular Nerves Before Total Knee Arthroplasty: Study Protocol for a Prospective Randomized Controlled Trial.

Cardiovascular and interventional radiology·2026

Behavioral recovery and motor reinnervation outcomes after peripheral nerve transection with microsuture or nerve tape repair.

Journal of neuroscience methods·2026

Multi-epitope design against emerging nipah virus towards peptide vaccine development.

Bioinformation·2026

Isolated trigeminal neuropathy as an initial manifestation of chronic inflammatory demyelinating polyradiculoneuropathy: A case report.

Radiology case reports·2026

Effect of multidimensional perioperative factors on postoperative delayed neurocognitive recovery in elderly patients undergoing single-port video-assisted thoracoscopic lobectomy: A prospective cohort study.

Current problems in surgery·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us