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Novel phenolate salts of bioactive agents: Cannabidiol phenolate salts

Pulikanti Guruprasad Reddy1, Ayala Bar-Hai1, Amnon Hoffman1

  • 1School of Pharmacy-Faculty of Medicine, The Hebrew University of Jerusalem, and Centre for Cannabis Research and the Institute of Drug Research, The Alex Grass Centre for Drug Design and Synthesis, Jerusalem, Israel.

Bioorganic Chemistry
|October 19, 2023
PubMed
Summary

This study introduces novel metal and ammonium salts of cannabidiol (CBD) to improve its water solubility and bioavailability. These synthesized CBD salts show significantly enhanced solubility, offering a promising approach for pharmaceutical applications.

Keywords:
Bioactive phenolic compoundsCannabidiolCannabidiol alkali metal and ammonium saltsPharmacokinetics evaluationWater soluble salts

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