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131I dose coefficients for a reference population using age-specific models.

Pradeep Kumar Singh1, Hemant Kumar Patni1, Rahul Roy1

  • 1Internal Dosimetry Section, Radiation Safety Systems Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.

Journal of Radiological Protection : Official Journal of the Society for Radiological Protection
|October 19, 2023
PubMed
Summary
This summary is machine-generated.

This study estimates internal radiation doses from Iodine-131 (¹³¹I) exposure in the general public using age-specific biokinetic models. Results show dose coefficients are generally lower than previous estimates, with the thyroid being the primary contributor.

Keywords:
131I age-specific dose coefficientsFLUKApaediatric reference computational phantoms

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Area of Science:

  • Radiological Physics and Dosimetry
  • Internal Dosimetry
  • Radiation Protection

Background:

  • Accurate internal dose assessment for the public requires age-specific dose coefficients.
  • Iodine-131 (¹³¹I) is a significant radionuclide in radiological assessments, necessitating precise biokinetic modeling.

Purpose of the Study:

  • To estimate age-specific dose coefficients for ¹³¹I exposure in the general public.
  • To calculate total nuclear disintegrations and S values for various source and target regions.
  • To determine committed tissue equivalent doses and dose coefficients for different age groups.

Main Methods:

  • Utilized age-specific biokinetic models for iodine and 10 paediatric reference computational phantoms.
  • Performed Monte Carlo transport simulations using FLUKA code.
  • Estimated total nuclear disintegrations (ã(rS,τ)), S values, committed tissue equivalent doses (HT(τ)), and dose coefficients (e(τ)).

Main Results:

  • Thyroid source ã(rS,τ) values increase with age; S values decrease with age due to increased target mass.
  • Committed tissue equivalent doses (HT(τ)) generally decrease with age.
  • Ingestion dose coefficients are 63% higher than inhalation; thyroid contributes 96-99% to dose coefficients.

Conclusions:

  • Estimated dose coefficients for ¹³¹I are lower than previous ICRP reference values.
  • Derived values can improve internal dose estimations for public exposure scenarios involving ¹³¹I.
  • Interpolation of dose coefficients allows accurate dose evaluation for ¹³¹I therapy or emergencies.