Related Experiment Video
Updated: Jul 12, 2025

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
[Help, I can't burp! A brief overview and case discussion of retrograde cricopharyngeal dysfunction]
Daniel Runggaldier1,2, Ursula Colotto-Vith3,4, Daniel Pohl5
1Klinik für Otorhinolaryngologie, Head and Neck Surgery, Abt. für Phoniatrie und klinische Logopädie, Universitätsspital Zürich, Frauenklinikstrasse 24, 8091, Zürich, Schweiz. daniel.runggaldier@usz.ch.
Abstract:
In this short communication, we discuss the recently described syndrome of retrograde cricopharyngeal dysfunction (R-CPD) with its first description in 2019 by the laryngologist Dr. Bastian. Diagnosis is generally based on typical clinical symptoms, e.g., the inability to belch, a bloated abdomen and retrosternal gurgling noises. We also describe high-resolution esophageal manometry as a new tool to further secure the diagnosis of R‑CPD, as well as therapeutic options such as botulinum toxin injections in the cricopharyngeal muscle or cricopharyngeal myotomy and the published data thereon.
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