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Updated: Jul 12, 2025
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
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New insights in acute heart failure.
Ayu Asakage1, Alexandre Mebazaa2, Benjamin Deniau3
1Université de Paris Cité, Paris, France; INSERM UMR-S 942, Cardiovascular Markers in Stress Condition (MASCOT), Université de Paris Cité, Paris, France.
Presse Medicale (Paris, France : 1983)
|October 21, 2023
Summary
Acute heart failure (AHF) management focuses on systemic venous congestion, a key factor in symptoms and poor prognosis. Current strategies involve diuretics, ventilation, and guideline-directed therapies, with ongoing research into new medications.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Acute heart failure (AHF) presents diagnostic challenges and a poor prognosis globally.
- Systemic venous congestion is central to AHF pathophysiology, causing symptoms, organ dysfunction, and worsening outcomes.
Approach:
- This review synthesizes recent guidelines from major cardiology societies (ESC, AHA/ACC/HFSA).
- It analyzes findings from large randomized controlled trials (RCTs) on AHF management.
- Focus is placed on decongestive therapies and guideline-directed medical treatments.
Key Points:
- Diuresis with intravenous loop diuretics, potentially combined with thiazides, is the primary decongestive approach.
- Non-invasive ventilation is a key supportive therapy.
- Preventing unresolved congestion at discharge is crucial to avoid rehospitalization, particularly during the post-discharge vulnerable phase.
Conclusions:
- Updated guidelines emphasize guideline-directed oral medical therapies for AHF.
- Ongoing trials are evaluating novel agents like SGLT2 inhibitors and advanced decongestive protocols.
- This review provides a summary of the latest insights in AHF management based on current evidence.
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