Related Experiment Video
Updated: Jul 12, 2025
07:50
An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
2.8K
Catheter Directed Thrombectomy and Other Deep Venous Interventions in Cancer Patients
Mari Tanaka1, Rui Dai2, Animan Randhawa2
1Department of Radiology - Interventional Radiology, Massachusetts General Hospital, Boston, MA.
Techniques in Vascular and Interventional Radiology
|October 21, 2023
Summary
Treating cancer patients with deep venous thrombosis/venous thromboembolism (DVT/VTE) requires careful consideration due to bleeding risks. This review focuses on percutaneous treatment strategies for DVT/VTE in the iliocaval system for oncologic patients.
Area of Science:
- Vascular Medicine
- Interventional Radiology
- Oncology
Background:
- Cancer patients with deep venous thrombosis/venous thromboembolism (DVT/VTE) present unique treatment challenges.
- Standard anticoagulation therapy is often contraindicated due to elevated bleeding risks in this population.
- Limited outcome data and guidelines exist for managing DVT/VTE in oncologic patients.
Approach:
- This article reviews critical factors for planning percutaneous interventions in cancer patients with DVT/VTE.
- Focus is placed on the iliocaval venous system, a common site for DVT/VTE in this cohort.
- Considers the limitations of anticoagulation and thrombolytic agents due to bleeding concerns.
Key Points:
- Percutaneous treatment planning must balance efficacy with bleeding risk in cancer patients.
- Multidisciplinary discussion is essential for tailoring treatment to individual patient factors.
- The iliocaval system requires specific considerations for interventional approaches.
Conclusions:
- Personalized treatment strategies are crucial for managing DVT/VTE in cancer patients.
- Percutaneous interventions offer an alternative when standard therapies are limited.
- Further research and guideline development are needed for this complex patient group.
Related Concept Videos
01:29Venous Thrombosis III: Interprofessional Care
10
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
10
01:30Venous Thrombosis IV: Nursing Management
14
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
14
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
12
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
12
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
10
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
10
01:27Pulmonary Embolism III: Nursing Management
15
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
15
01:26Varicose Veins II: Diagnostic Studies and Interprofessional Care
14
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
14