Related Experiment Video
Updated: Jul 12, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
A short history of nasal polyposis
L de Gabory1, D Portmann2, M Kérimian3
1Service d'ORL et Chirurgie Cervico-Faciale, Centre François Xavier Michelet, CHU de Bordeaux, Bordeaux, France; Université de Bordeaux, Bordeaux 33000, France; Institut Georges Portmann, 114, avenue D'Ares, 33000 Bordeaux, France.
Abstract:
Nasal polyposis was initially considered a tumor, but came to be seen as a chronic inflammatory mucosal disease during the second half of the 20th century. Although pathogenesis remains unclear, this has not prevented progress in diagnosis and treatment, both surgical and medical, based on the hypotheses of chronic rhinosinusitis with type-2 inflammation and autoimmune inflammation maintained by the vestigial olfactory mucosa of the ethmoid.
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