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Related Concept Videos

Ovarian Cycle01:27

Ovarian Cycle

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The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
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Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
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The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
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The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
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Uterine Tubes01:16

Uterine Tubes

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The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
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Related Experiment Video

Updated: Jul 12, 2025

A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse

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Towards decoding the space-time continuum of pregnancy.

Kristin Thiele1, Petra Clara Arck1

  • 1Division of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Trends in Immunology
|October 22, 2023
PubMed
Summary

Pregnancy involves complex maternal adaptations. Spatially-resolved transcriptomics allows detailed study of these changes during early mammalian pregnancy and fetal development.

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Last Updated: Jul 12, 2025

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Area of Science:

  • Reproductive biology
  • Developmental biology
  • Genomics

Background:

  • Pregnancy is a complex biological process involving dynamic maternal adaptations.
  • Understanding these adaptations is crucial for reproductive health and developmental biology.
  • Previous methods limited detailed, site-specific analysis of these dynamic changes.

Purpose of the Study:

  • To decode dynamic adaptations during early mammalian pregnancy.
  • To comprehensively analyze changes throughout fetal development using advanced techniques.

Main Methods:

  • Spatially-resolved transcriptomic analyses were employed.
  • This technique allows for high-resolution gene expression profiling at specific tissue locations.

Main Results:

  • The study successfully decoded dynamic adaptations during early pregnancy.
  • Comprehensive transcriptomic data was obtained throughout fetal development.

Conclusions:

  • Spatially-resolved transcriptomics is a powerful tool for studying pregnancy.
  • This approach provides unprecedented insights into maternal and fetal development.