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Updated: Jul 12, 2025

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Accelerated 2D Cartesian MRI with an 8-channel local B0 coil array combined with parallel imaging.
Rui Tian1, Martin Uecker2,3,4,5, Mathias Davids6,7
1High-Field MR center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.
This study optimizes magnetic field modulation in Magnetic Resonance Imaging (MRI) using a local coil array. The new method significantly speeds up 2D Cartesian scans, achieving threefold and eightfold acceleration without visible artifacts.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Medical Physics
- Biomedical Engineering
Background:
- Magnetic Resonance Imaging (MRI) utilizes linear gradients and radiofrequency receiver sensitivity profiles for spatial encoding, leading to long scan times.
- Cartesian MRI, a common clinical technique, can be accelerated using parallel imaging and rapid magnetic field modulation during signal readout.
Purpose of the Study:
- To investigate an optimized modulation scheme for sampling efficiency using an 8-channel local coil array to accelerate 2D Cartesian MRI scans.
- To explore nonlinear encoding for faster MRI acquisition.
Main Methods:
- An 8-channel local coil array was employed to carry sinusoidal currents during signal readout for accelerating 2D Cartesian scans.
- MRI sampling theory based on reproducing kernel Hilbert space was used to analyze nonlinear encoding efficiency.
- A field calibration method with current monitors and the ESPIRiT algorithm facilitated image reconstruction.
- Various modulation field shapes, aliasing control, and frequencies were evaluated for optimization, alongside safety assessments.
Main Results:
- The optimal modulation field for the local coil array approximated a linear gradient field for 2D Cartesian MRI.
- The developed field calibration technique enabled threefold and eightfold acceleration of in vivo scans.
- Accelerated scans were achieved free of visible artifacts, with and without SENSE (Sensitivity Encoding).
- Safety evaluations confirmed the in vivo scans were safe.
Conclusions:
- The study presents a nonlinear encoding analysis tool, a field calibration method, and safety evaluation procedures for accelerating MRI.
- These advancements, demonstrated through in vivo scans, significantly contribute to increasing MRI scan speed using local coil arrays.
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