Related Experiment Video
Updated: Jul 12, 2025

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
Published on: October 18, 2024
Extracorporeal life support use in limited lung function: a narrative review
João Santos Silva1, Daniel Cabral2, Paulo Almeida Calvinho1
1Serviço de Cirurgia Cardiotorácica, Hospital de Santa Marta, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.
Extracorporeal life support (ECLS) offers solutions for complex thoracic surgeries when single lung ventilation is challenging. Venovenous extracorporeal membrane oxygenation is key for supporting lung function during these critical procedures.
Area of Science:
- Cardiovascular and Respiratory System Support
- Thoracic Surgery Innovations
- Extracorporeal Life Support Technologies
Background:
- Thoracic surgery often involves complex scenarios requiring cardiorespiratory support.
- Advancements in technology have led to diverse extracorporeal life support (ECLS) systems.
- Difficult or impossible single lung ventilation presents a significant challenge in thoracic procedures.
Purpose of the Study:
- To review the application of various extracorporeal life support (ECLS) modalities in thoracic surgery.
- To highlight ECLS as a solution for complex surgeries with ventilation challenges.
- To describe ECLS use in patients unable to tolerate single lung ventilation.
Main Methods:
- Literature review conducted using specific search terms.
- Articles selected based on predefined inclusion criteria.
- Focus on studies detailing ECLS in thoracic surgery and pulmonary resection.
Main Results:
- Venovenous extracorporeal membrane oxygenation is the most utilized ECLS modality for lung support.
- ECLS is beneficial in lung resections post-pneumonectomy, severe hypercapnia, airway surgery, and trauma.
- Successful ECLS application requires multidisciplinary collaboration, patient selection, and meticulous surgical planning.
Conclusions:
- Understanding ECLS techniques is crucial for thoracic surgeons.
- ECLS should be considered for complex thoracic cases with ventilation difficulties or emergencies.
- ECLS provides a vital cardiorespiratory support option in challenging surgical situations.
More Related Videos
09:31Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
09:54Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
Related Concept Videos
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-III