Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Semiology matters: diagnosing functional seizures beyond the EEG.

Neurologia i neurochirurgia polska·2026

Same author

Subcortical Stimulation for Functional Brain Mapping: A Systematic Review.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026

Same author

Efficacy of cenobamate in tumor-related epilepsy.

Epileptic disorders : international epilepsy journal with videotape·2025

Same author

Acute Symptomatic Seizures During CAR T-Cell Therapy for Hematologic Malignancies: Tri-Site Mayo Clinic Experience.

Neurology·2025

Same author

Seizures in Cerebral Amyloid Angiopathy: A Systematic Review and Meta-Analysis.

Neurology. Clinical practice·2025

Same author

Pupillary constriction on stimulation of the parietal cortex-A novel finding.

Epileptic disorders : international epilepsy journal with videotape·2024

Search research articles

Related Experiment Video

Updated: Jul 12, 2025

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Published on: November 19, 2017

Can we improve electrocorticography using a circular grid array in brain tumor surgery?

Brin E Freund¹, Wendy J Sherman¹, David S Sabsevitz²

¹Department of Neurology, Mayo Clinic College of Medicine, Mayo Clinic, Jacksonville, FL, United States of America.

Biomedical Physics & Engineering Express

|October 23, 2023

Summary

This summary is machine-generated.

A novel circular electrode grid improves brain tumor surgery by enhancing electrocorticography (iECoG) for precise mapping and resection, leading to better patient outcomes.

Keywords:

brain electrocorticography electrode grid seizures surgery tumor

More Related Videos

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Published on: June 26, 2012

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

Related Experiment Videos

Last Updated: Jul 12, 2025

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Published on: November 19, 2017

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Published on: June 26, 2012

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

Area of Science:

Neurosurgery
Neurophysiology
Biomedical Engineering

Background:

Intraoperative electrocorticography (iECoG) is crucial for localizing the epileptogenic zone in brain tumor surgeries.
Current iECoG electrode arrays have limitations that can complicate functional brain mapping and surgical outcomes.
Seizures or after-discharges during surgery can hinder accurate interpretation and lead to premature termination of procedures.

Approach:

Developed a novel, higher-density, 360-degree hollow circular electrode grid array for iECoG.
Designed for continuous EEG recording during surgical intervention and electrical stimulation mapping.
Evaluated the performance of the circular grid against traditional linear strip electrodes.

Key Points:

The circular grid demonstrated significantly quicker recovery of post-operative motor deficits (2.4 vs. 9 days).
Achieved more extensive tumor resection (92.0% vs. 77.6%) with the circular grid.
Showed less reduction in Karnofsky Performance Scale postoperatively and greater sensitivity in recording afterdischarges.

Conclusions:

Customized, higher-density electrode grids like the circular array offer significant advantages over commercially available options.
The novel circular iECoG grid enhances precision in functional brain mapping and safe tumor resection.
This technology has the potential to improve survival and functional outcomes for patients with epilepsy and brain tumors.