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ICTV Virus Taxonomy Profile: Tosoviridae 2023
Yuri I Wolf1, Mart Krupovic2, Jens H Kuhn3
1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
The Journal of General Virology
|October 24, 2023
Summary
Tosoviridae viruses, found in turtles, possess a two-segment RNA genome encoding key proteins like nucleoprotein and RNA-directed RNA polymerase. This summary details the International Committee on Taxonomy of Viruses report on this viral family.
Area of Science:
- Virology
- Molecular Biology
- Taxonomy
Background:
- Tosoviridae represents a family of negative-sense RNA viruses.
- These viruses have been identified in turtle species.
- Their genomes are approximately 12.3 kb in total size.
Purpose of the Study:
- To summarize the International Committee on Taxonomy of Viruses (ICTV) report on the Tosoviridae family.
- To provide an overview of the genomic structure and encoded proteins of Tosoviridae.
Main Methods:
- Review and summarization of the ICTV report on Tosoviridae.
- Analysis of the genomic organization and protein-coding potential of the virus family.
Main Results:
- The Tosoviridae genome comprises two segments with ambisense open reading frames (ORFs).
- The small (S) segment encodes a nucleoprotein (NP) and a glycoprotein precursor (GPC).
- The large (L) segment encodes an L protein (RNA-directed RNA polymerase domain) and a zinc-binding (Z) protein.
Conclusions:
- The ICTV report provides a standardized classification and description of the Tosoviridae family.
- Understanding the genomic structure is crucial for further research into Tosoviridae replication and pathogenesis.
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