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Related Experiment Video

Updated: Jul 12, 2025

The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration
12:21

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Necrotizing Otitis Externa: A Proposal for Diagnostic and Therapeutic Approach.

Marília Batista Costa1, Ektor Tsuneo Onishi1

  • 1Department of Otorhinolaryngology - Head and Neck Surgery, Universidade Federal de São Paulo, Escola Paulista de Medicina, Sao Paulo, SP, Brazil.

International Archives of Otorhinolaryngology
|October 25, 2023
PubMed
Summary

Necrotizing otitis externa management was standardized with a new protocol. This protocol addresses increasing cases and aims to improve patient outcomes in this serious ear infection.

Keywords:
diabetes mellitusexternal otitisosteomyelitisotolaryngologyskull base

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Area of Science:

  • Otolaryngology
  • Infectious Diseases

Background:

  • Necrotizing otitis externa (NOE) significantly impacts patient quality of life.
  • NOE incidence is rising, with evolving patient demographics and management inconsistencies.

Purpose of the Study:

  • To establish a practical and effective care protocol for standardizing NOE diagnosis and treatment.

Main Methods:

  • Retrospective cohort study of 34 NOE patients (36 ears) from January 2015 to December 2020.
  • Data analysis included patient demographics, pathogens, resistance patterns, imaging, treatment, and outcomes.

Main Results:

  • The study identified Pseudomonas aeruginosa as the most common pathogen (50%), with 35% resistance to ciprofloxacin.
  • Most patients (91%) required hospitalization; ceftazidime was the most prescribed antibiotic.
  • Complications occurred in 35% of patients, including facial paralysis (12%) and mortality (9%).

Conclusions:

  • A diagnostic and therapeutic protocol for necrotizing otitis externa was developed.
  • This protocol serves as a dynamic tool for effective NOE management, requiring ongoing updates.