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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Preventing new-onset heart failure: Intervening at stage A
Bharathi Upadhya1, Shriram Hegde2, Manasi Tannu1
1Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Preventing heart failure (HF) in Stage A patients requires early risk factor awareness and lifestyle changes. Comprehensive strategies, including managing blood pressure, diabetes, and lipids, are crucial for primordial HF prevention.
Area of Science:
- Cardiology
- Public Health
- Preventive Medicine
Background:
- Heart failure (HF) prevention is a critical public health issue.
- Stage A HF patients lack symptoms but face HF development risk.
- Current detection strategies for Stage A patients are insufficient.
Purpose of the Study:
- To highlight the need for comprehensive strategies for Stage A HF prevention.
- To emphasize early risk factor identification and intervention.
- To advocate for primordial and primary HF prevention strategies.
Main Methods:
- Review of current HF prevention guidelines and risk factors.
- Identification of Stage A HF patient heterogeneity and risk stratification needs.
- Discussion of comprehensive prevention strategies including lifestyle and medical management.
Main Results:
- Stage A patients are diverse with varying HF risks.
- Intensive blood pressure, glycemic, and lipid management are key.
- Heart-healthy behaviors (Life's Essential 8) are vital.
- Nontraditional risk factors (e.g., CKD, AFib, genetic susceptibility) increase HF risk.
- Biomarkers, imaging, and echocardiography can enhance risk prediction.
Conclusions:
- Public awareness of HF risk factors and early healthy lifestyle choices are paramount.
- Recognizing HF risk-enhancing factors is essential for early intervention.
- Policies must extend beyond secondary prevention to encompass primordial and primary HF prevention.
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