Related Experiment Video

Updated: Jun 28, 2026

Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

10.0K

Enhancing diagnostic accuracy in common human poxvirus infections during mpox outbreak: A dermoscopy review

Xu Li1,2, Mutong Zhao3, Yanfei Li1,2

  • 1Department of Dermatology, The First Hospital of Hohhot, Hohhot, China.

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|October 26, 2023
PubMed

Insights

Poxvirus infections like mpox can present with unusual skin lesions. Dermoscopy aids dermatologists in diagnosing these poxvirus (Poxviridae family) infections, including mpox, orf, milker's nodule, and molluscum contagiosum.

Area of Science:

  • Dermatology
  • Virology
  • Infectious Diseases

Background:

  • Poxviruses (Poxviridae family) are significant human pathogens, with smallpox eradicated but mpox cases resurging.
  • Poxvirus infections can manifest with atypical cutaneous lesions beyond typical presentations.
  • Dermoscopy is increasingly vital for diagnosing skin conditions, including viral infections.

Purpose of the Study:

  • To summarize the clinical and dermoscopic features of various human poxvirus infections.
  • To highlight the utility of dermoscopy in identifying poxvirus-related cutaneous lesions.
  • To provide a reference for dermatologists managing poxvirus outbreaks.

Main Methods:

  • Review of clinical and dermoscopic findings of human poxvirus infections.
  • Inclusion of representative cases of mpox, orf, milker's nodule, and molluscum contagiosum.
  • Focus on characteristic dermoscopic patterns for each poxvirus type.

Main Results:

  • Poxvirus infections exhibit diverse clinical presentations, often with characteristic dermoscopic features.
  • Dermoscopy can differentiate between various poxvirus lesions, aiding in accurate diagnosis.
  • Specific dermoscopic criteria are presented for mpox, orf, milker's nodule, and molluscum contagiosum.

Conclusions:

  • Dermoscopy is an essential tool for the diagnosis of cutaneous poxvirus infections.
  • Recognizing atypical presentations and utilizing dermoscopy improves patient management.
  • Understanding dermoscopic features aids in distinguishing between different poxvirus (Poxviridae family) infections.
Keywords:
dermoscopydiagnosisinfectionmpoxpoxvirus

More Related Videos

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.4K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

114

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...