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Smartphone-Based Digital Eczema Education Program for Atopic Dermatitis in Children Aged 0 to 6 Years: Multicenter,

Huan Yang¹, Hong Shu², Liu-Hui Wang³

¹Department of Dermatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, NO.136 Zhongshan 2nd Road, Yuzhong District, Chongqing, 400014, China, +86-23-63638830.

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Summary

A smartphone-based education program significantly reduced short-term relapse rates in children with atopic dermatitis (AD). This digital approach offers a scalable way to improve caregiver management and prevent flares in pediatric AD patients.

Keywords:

atopic dermatitis caregiver engagement digital education multicenter study pediatric dermatology randomized controlled trial relapse prevention self-management smartphone-based intervention telemedicine portal

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Area of Science:

Dermatology
Digital Health
Pediatrics

Background:

Atopic dermatitis (AD) is a prevalent chronic skin condition in children, posing significant health and economic challenges.
Conventional patient education for AD is resource-intensive and limited in scalability and personalization.
Digital tools offer potential for improved AD management, but evidence in young children is scarce.

Purpose of the Study:

To evaluate the efficacy of a smartphone-based educational program in reducing relapse rates in young children (0-6 years) with moderate-to-severe AD.
To compare the digital intervention against standard outpatient consultation for pediatric AD management.

Main Methods:

A multicenter, randomized controlled trial involving 615 children with moderate-to-severe AD.
The intervention group received a 12-week smartphone-based digital education program (WeChat platform) alongside standard care.
The control group received standard face-to-face consultation only.

Main Results:

The digital education group showed a significantly lower 12-week relapse rate (16.6%) compared to the control group (24.0%; P=.02).
Relapse-free survival was superior in the digital group over the first 100 days (HR 0.688; P=.03).
High caregiver adherence (58.0% weekly use) was observed, though long-term effects beyond 12 weeks were not significant.

Conclusions:

Smartphone-based patient-caregiver education effectively reduces short-term relapse risk in pediatric moderate-to-severe AD.
This scalable digital intervention is a feasible adjunct to standard care, improving caregiver recognition and early management of flares.
Further research should explore sustained engagement and long-term cost-effectiveness in diverse populations.