Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Defect-insensitive bound states in the continuum in antisymmetric trapezoid metasurfaces in the visible range.

Nanophotonics (Berlin, Germany)·2025
Same author

Ultrasensitive refractometric sensing via centimeter-scale metasurfaces with spatially gradient geometry generated by elastomer mechanical stretching.

Optics express·2024
Same author

Defect-insensitive cylindrical surface lattice resonance array and its batch replication for enhanced immunoassay.

Microsystems & nanoengineering·2024
Same author

Multi-biomarker combination detection system for diagnosis and classification of dry eye disease by imaging of a multi-channel metasurface.

Biosensors & bioelectronics·2024
Same author

Application of Multi-Criteria Decision-Making Analysis to Rural Spatial Sustainability Evaluation: A Systematic Review.

International journal of environmental research and public health·2022
Same author

Ultrasensitive Molecular Detection at Subpicomolar Concentrations by the Diffraction Pattern Imaging with Plasmonic Metasurfaces and Convex Holographic Gratings.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2022

Related Experiment Video

Updated: Jul 12, 2025

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
07:28

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

10.8K

Cost-Effective Nanophotonic Metasurfaces with Spatially Gradient Structures for Ultrasensitive Imaging-Based

Guohua Li1, Baohua Wen1, Ji Yang1

  • 1School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.

Small Methods
|October 26, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces a novel nanophotonic metasurface sensing system that eliminates the need for spectrometers. This imaging-based approach offers ultrahigh sensitivity for refractive index sensing, making advanced diagnostics more accessible.

Keywords:
imaging-based sensing schememetasurfacenanophotonicrefractometric sensors

More Related Videos

Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces
09:33

Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces

Published on: June 7, 2019

6.3K
Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
06:15

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

Published on: June 16, 2023

1.9K

Related Experiment Videos

Last Updated: Jul 12, 2025

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
07:28

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

10.8K
Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces
09:33

Demonstration of Equal-Intensity Beam Generation by Dielectric Metasurfaces

Published on: June 7, 2019

6.3K
Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
06:15

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

Published on: June 16, 2023

1.9K

Area of Science:

  • Nanophotonics
  • Metasurface Technology
  • Biosensing

Background:

  • Nanophotonic metasurfaces offer label-free, noninvasive, real-time sensing for biomedical and environmental applications.
  • Current limitations include reliance on complex instruments and costly, time-consuming fabrication processes.

Purpose of the Study:

  • To develop an advanced imaging-based sensing scheme using spatially gradient metasurfaces.
  • To overcome the limitations of conventional metasurface sensing by eliminating the need for spectrometers.

Main Methods:

  • Integration of a spatially gradient metasurface with an imaging-based sensing scheme.
  • Fabrication of the metasurface using nanoimprint lithography with a reusable cyclic olefin copolymer template.
  • Analysis of grayscale image intensity changes to determine the refractive index of the surrounding medium.

Main Results:

  • Achieved ultrahigh imaging-based sensitivity of 3321 pixels/refractive index unit, surpassing conventional spectrometers.
  • Demonstrated the reliability and reusability of the fabrication template, reducing costs.
  • Verified the proposed method through theoretical analysis and experimental validation.

Conclusions:

  • The developed imaging-based metasurface sensor offers a cost-effective and highly sensitive alternative to traditional methods.
  • The reusable template technology significantly lowers fabrication expenses for nanophotonic sensing elements.
  • This technology holds promise for point-of-care, real-time, and on-site biosensing applications.