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Related Experiment Video

Updated: Jul 12, 2025

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

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Zero-fluoroscopy ablation with multielectrode pulse field ablation system: Case series.

Martin Rauber1,2, Martin Manninger2, Anna-Sophie Eberl2

  • 1Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Pacing and Clinical Electrophysiology : PACE
|October 27, 2023
PubMed
Summary

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Pulsed Field Ablation With a Variable Loop Circular Catheter in Atrial Fibrillation: Acute Outcomes From the VARIPURE Multicenter Study.

Heart rhythm·2026
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Catheter ablation of atrial fibrillation in transthyretin and light-chain cardiac amyloidosis: results from the multicentre AMYL-AF study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
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Inflammatory Biomarkers and Their Associations with Arrhythmic Burden Following SGLT2-I Treatment in Chronic Heart Failure-A Subanalysis of the ERASe Trial.

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Standardized processing of explanted hearts after stereotactic arrhythmia radiotherapy (Bio-STAR): a STOPSTORM framework and first human findings.

European heart journal open·2026
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Diversity, equity, and inclusion in arrhythmia care: a European Heart Rhythm Association survey.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
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Association Between Contact Force and Acute Lesion Effectiveness in Focal Pulsed Field Ablation.

Journal of cardiovascular electrophysiology·2026

Pulse field ablation (PFA) offers a new way to treat atrial fibrillation. This study shows a zero-fluoroscopy approach using intracardiac echocardiography is feasible with the Farapulse PFA system, reducing radiation exposure.

Area of Science:

  • Cardiology
  • Medical Devices
  • Electrophysiology

Background:

  • Pulse field ablation (PFA) is an emerging nonthermal ablation technique for atrial fibrillation treatment.
  • Current PFA procedures often involve significant radiation exposure due to reliance on fluoroscopy and lack of integrated 3D electroanatomical mapping.
  • Minimizing radiation is crucial for patient safety and procedural efficiency.

Purpose of the Study:

  • To present a novel zero-fluoroscopy workflow for PFA using intracardiac echocardiography (ICE).
  • To evaluate the feasibility of this approach in a case series of patients undergoing PFA for atrial fibrillation.
  • To demonstrate the utility of the Farapulse PFA system in a zero-fluoroscopy setting.

Main Methods:

  • A case series of three patients undergoing PFA for atrial fibrillation was retrospectively analyzed.
Keywords:
Farapulsefluoroless ablationintracardiac echocardiographypulse field ablationzero-fluoroscopy

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Last Updated: Jul 12, 2025

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  • Intracardiac echocardiography (ICE) was used for catheter navigation and visualization, eliminating the need for fluoroscopy.
  • The Farapulse PFA system was employed within this zero-fluoroscopy protocol.

    • Main Results:

    • The zero-fluoroscopy approach utilizing ICE and the Farapulse PFA system was successfully implemented in all three patients.
    • The workflow demonstrated feasibility for catheter manipulation and ablation delivery without fluoroscopic guidance.
    • This approach offers a potential strategy to significantly reduce or eliminate radiation exposure during PFA procedures.

    Conclusions:

    • A zero-fluoroscopy workflow combining intracardiac echocardiography and the Farapulse PFA system is feasible for atrial fibrillation ablation.
    • This innovative approach has the potential to enhance patient safety by minimizing radiation exposure.
    • Further studies are warranted to validate and optimize this technique for broader clinical application.