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Updated: Jul 12, 2025

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
Published on: January 20, 2022
HumanLectome, an update of UniLectin for the annotation and prediction of human lectins
Boris Schnider1,2, Yacine M'Rad1,2, Jalaa El Ahmadie1,2,3
1Proteome Informatics Group, SIB Swiss Institute of Bioinformatics, CH-1211 Geneva, Switzerland.
Abstract:
The UniLectin portal (https://unilectin.unige.ch/) was designed in 2019 with the goal of centralising curated and predicted data on carbohydrate-binding proteins known as lectins. UniLectin is also intended as a support for the study of lectomes (full lectin set) of organisms or tissues. The present update describes the inclusion of several new modules and details the latest (https://unilectin.unige.ch/humanLectome/), covering our knowledge of the human lectome and comprising 215 unevenly characterised lectins, particularly in terms of structural information. Each HumanLectome entry is protein-centric and compiles evidence of carbohydrate recognition domain(s), specificity, 3D-structure, tissue-based expression and related genomic data. Other recent improvements regarding interoperability and accessibility are outlined.
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