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Preparing ethical review systems for emergencies: next steps.

Katharine Wright1, Nic Aagaard2, Amr Yusuf Ali3

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Summary

Ethical review systems must learn from COVID-19 research to prepare for future pandemics. Key recommendations include fostering collaboration, adapting processes, and advocating for increased resources.

Keywords:
Ethical preparedness; research ethics; ethical review; rapid review; COVID-19; infectious disease outbreaks; low- and middle-income countries

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Area of Science:

  • Public Health
  • Medical Ethics
  • Research Administration

Background:

  • The COVID-19 pandemic highlighted vulnerabilities in ethical review systems globally.
  • Existing ethical review frameworks require adaptation to meet the demands of large-scale, rapid research during health crises.

Purpose of the Study:

  • To identify key lessons from COVID-19 research for enhancing ethical review preparedness.
  • To propose actionable recommendations for improving ethical review systems for future pandemics.

Main Methods:

  • Analysis of experiences and recommendations from ethical review representatives across over twenty countries.
  • Synthesis of best practices and areas for improvement in pandemic research ethics.

Main Results:

  • Strengthened relationships across the research ecosystem are crucial.
  • A demonstrated willingness to reform and adapt systems and processes is essential.
  • Robust advocacy for better resourcing of ethical review functions is necessary.

Conclusions:

  • Ethical review systems must proactively adapt based on pandemic research experiences.
  • Enhanced collaboration, systemic flexibility, and adequate funding are vital for future pandemic preparedness.