Related Experiment Video

Updated: Jul 12, 2025

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

5.3K

Atherogenic Index of Plasma Predicts Obstructive Coronary Artery Disease in Patients with Stable Angina Pectoris

Haci Ali Kurklu1, Turkan Seda Tan2, Nil Ozyuncu2

  • 1Department of Cardiovascular Medicine, Ankara Etlik Research Hospital, Ankara 06590, Turkey.

Diagnostics (Basel, Switzerland)
|October 28, 2023
PubMed

Insights

The atherogenic index of plasma (AIP) can help identify patients with obstructive coronary artery disease (CAD). Higher AIP levels are linked to a greater risk of significant coronary artery stenosis.

Area of Science:

  • Cardiovascular Medicine
  • Biochemical Risk Assessment
  • Coronary Artery Disease

Background:

  • Chronic coronary syndrome involves risk factors like dyslipidemia and hypertension.
  • The atherogenic index of plasma (AIP) is a known biochemical risk factor for coronary artery disease (CAD).

Purpose of the Study:

  • To evaluate the effectiveness of the atherogenic index of plasma (AIP) in estimating obstructive CAD.
  • To determine if AIP can serve as a predictive marker for significant coronary artery stenosis.

Main Methods:

  • Included 345 patients undergoing coronary angiography.
  • Defined obstructive CAD as ≥50% stenosis in one or more coronary vessels.
  • Analyzed AIP values in relation to obstructive CAD using univariable and multivariable analyses, including ROC analysis.

Main Results:

  • Patients with obstructive CAD had significantly higher mean AIP values (0.58 ± 0.27) compared to those without (0.49 ± 0.26).
  • AIP showed a significant association with obstructive CAD (OR: 3.74).
  • An AIP cut-off value of 0.49 was identified, with higher values indicating ≥50% coronary artery stenosis.

Conclusions:

  • The atherogenic index of plasma (AIP) is a valuable parameter for assessing cardiovascular risk in patients with stable angina.
  • AIP can be effectively used to estimate the presence of obstructive coronary artery disease.
Abstract

Keywords:
atherogenic index of plasmacardiovascular risk factorcoronary artery diseasecoronary artery stenosis

More Related Videos

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

3.9K
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

5.0K

Related Concept Videos

Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
7
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
9
Angina I: Introduction01:30

Angina I: Introduction

Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
12
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
17
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.3K
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
9