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Updated: Jul 12, 2025

Study of the Functions and Activities of Neuronal K-Cl Co-Transporter KCC2 Using Western Blotting
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Cannabidiol Modulates M-Type K+ and Hyperpolarization-Activated Cation Currents

Yen-Chin Liu1,2,3, Edmund Cheung So4, Sheng-Nan Wu5,6,7

  • 1Department of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.

Biomedicines
|October 28, 2023
PubMed
Summary

Cannabidiol (CBD) affects key ion channels in pituitary cells, decreasing M-type potassium and hyperpolarization-activated cation currents. These CBD effects on ionic currents are independent of cannabinoid or opioid receptors.

Keywords:
M-type K+ currentcannabidiol (CBD)erg-mediated K+ currenthyperpolarization-activated cation currentpituitary cellvoltage-gated Na+ current

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