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Diffuse Large B-Cell lymphoma Misdiagnosed as a Hematoma: Case Report
1Department of Plastic and Reconstructive Surgery, Busan Paik Hospital, School of Medicine, Inje University, Busan 47392, Republic of Korea.
Medicina (Kaunas, Lithuania)
|October 28, 2023
Summary
Diffuse large B-cell lymphoma (DLBCL) can mimic a hematoma, delaying diagnosis. Vigilance for malignancy is crucial in soft tissue swelling cases for better patient outcomes.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin's lymphoma subtype.
- DLBCL presents diagnostic challenges due to varied clinical manifestations.
- This case highlights diagnostic complexities in DLBCL.
Observation:
- A 76-year-old male presented with periorbital swelling and ecchymosis post-trauma.
- Initial CT suggested extraconal hematoma, leading to incision and drainage.
- Persistent symptoms and lesion enlargement prompted excisional biopsy.
Findings:
- Pathologic examination confirmed diffuse large B-cell lymphoma (DLBCL).
- The mass showed a diffuse infiltrate of lymphocytes.
Implications:
- Misdiagnosis as hematoma delayed DLBCL treatment.
- Considering malignancy in unresponsive swelling is critical.
- Timely diagnosis of DLBCL improves prognosis for this aggressive lymphoma.
