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Muscle Recovery and Fatigue

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Recovery after Running an "Everesting" Mountain Ultramarathon.

Anton Ušaj1, Jon Lihteneger Vidmajer1, Sonja Lojen2

  • 1Laboratory of Biodynamics, Faculty of Sport, University of Ljubljana, 1000 Ljubljana, Slovenia.

Life (Basel, Switzerland)
|October 28, 2023
PubMed
Summary

Mountain ultramarathon recovery involves more than muscle damage. Prolonged reduced performance is linked to cardiorespiratory and metabolic changes, including decreased VO2peak and increased energy cost, lasting up to a month.

Keywords:
carbohydrate oxidation rateenergetic costlactate thresholdrelative running intensityrespiratory fatigue

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Area of Science:

  • Exercise Physiology
  • Sports Science
  • Biomedical Science

Background:

  • Reduced performance post-ultramarathon is common.
  • Traditional markers like creatine kinase and C-reactive protein incompletely explain prolonged fatigue.
  • Need for deeper investigation into physiological recovery mechanisms.

Observation:

  • A single runner (24 y/o, 70kg, 22 BMI, 74 mL∙min-1∙kg-1 VO2peak) completed the Everesting ultramarathon (9349m vertical) in 18:22.
  • Data collected over a 2-month preparation and 1-month recovery period.
  • Runner experienced initial performance decrease explained by elevated muscle damage and inflammation markers.

Findings:

  • The second, longer recovery phase showed decreased performance linked to reduced lactate threshold and VO2peak (21% and 17% respectively).
  • Increased energetic cost of running (15%), higher endogenous carbohydrate oxidation (87%), elevated lactate (170%), and respiratory muscle fatigue were observed.
  • These cardiorespiratory and metabolic alterations persisted for up to one month post-race.

Implications:

  • Cardiorespiratory and metabolic factors are crucial for understanding prolonged recovery after extreme endurance events.
  • Standard blood markers are insufficient for assessing the full recovery spectrum.
  • This case study highlights the need for comprehensive physiological assessments in ultra-endurance athletes.