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AMPK activation induces immunogenic cell death in AML

Johanna Mondesir1,2, Margherita Ghisi3,4, Laura Poillet3,4

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.

Blood Advances
|October 30, 2023
PubMed
Summary

Activation of adenosine 5'-monophosphate-activated protein kinase (AMPK) using GSK621 enhances immune responses against acute myeloid leukemia (AML). This approach promotes immunogenic cell death, offering a new avenue for AML immunotherapy.

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