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Prevention and control of COVID-19 outbreak in a hemodialysis center
Camilo Alberto González González1, Kelly Rocío Chacón Acevedo2, Ana Maria Arana1
1Unidad Renal, Clínica Colsanitas, Bogotá, Colombia.
Insights
The COVID-19 infection rate in hemodialysis patients was high, with a 30.2% cumulative incidence. Strict biosafety measures are crucial for preventing outbreaks in dialysis units.
Area of Science:
- Nephrology
- Infectious Diseases
- Epidemiology
Background:
- Controlling SARS-CoV-2 in hemodialysis (HD) units presents significant challenges.
- Patients with chronic kidney disease (CKD) on HD are a vulnerable population for severe COVID-19 outcomes.
Purpose of the Study:
- To characterize the clinical presentation and outcomes of COVID-19 in CKD patients undergoing HD.
- To determine the incidence, prevalence, and case-fatality rates of SARS-CoV-2 infection in a Colombian HD unit.
Main Methods:
- Prospective observational study conducted from March 2020 to January 2021.
- Screening included RT-PCR and anti-SARS-CoV-2 IgG/IgM antibody testing for all patients and staff.
- Epidemiological metrics such as incidence, prevalence, and case-fatality rates were calculated.
Main Results:
- Identified 55 COVID-19 cases in patients and 9 in health personnel.
- The cumulative incidence of infection was 30.2%, with a population seroprevalence of 24.9%.
- The case-fatality rate among infected patients was 9.1%; common symptoms included fever, cough, and myalgia.
Conclusions:
- The study revealed a high incidence of SARS-CoV-2 infection within the hemodialysis unit.
- Emphasizes the critical need for stringent biosafety protocols to mitigate outbreaks in HD settings.
Background:
The prevention and control of SARS-CoV-2 infection in hemodialysis (HD) units is challenging.
Aim:
To describe the clinical characteristics and outcome of patients with chronic kidney disease (CKD) on HD with COVID-19, between March 2020 and January 28, 2021, attending a single HD unit in Bogotá, Colombia.
Material And Methods:
In this prospective observational study, incidence, prevalence, and case-fatality rate were estimated, including screening results with RT-PCR and anti-SARS-CoV-2 IgG and IgM antibodies in all patients and health personnel in the HD unit.
Results:
Among patients and health workers, 55 and 9 cases of COVID-19 were identified, respectively. The median age of patients was 63 years (84% males). Fifty five percent of patients were symptomatic, with fever, cough and/or myalgia. The most common comorbidities were hypertension, type 2 diabetes mellitus, and coronary heart disease. The cumulative incidence of infection was 30.2%, population seroprevalence was 24.9%, and fatality was 9.1%.
Conclusions:
The incidence of SARS-CoV-2 infection in this HD unit was high. Strict biosafety protocols are required to prevent outbreaks.
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