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Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Light mixed-supervised segmentation for 3D medical image data.

Hongxu Yang1, Tao Tan1, Pal Tegzes2

  • 1GE Healthcare, Eindhoven, The Netherlands.

Medical Physics
|November 1, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces a mixed-supervised learning method for 3D medical image segmentation, significantly reducing annotation effort. The approach achieves stable and accurate segmentation even with relaxed bounding box annotations, outperforming state-of-the-art methods.

Keywords:
3D medical imagescontrastive learningmixed-supervised learningrelaxed bounding box

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Area of Science:

  • Medical Imaging
  • Computer Vision
  • Machine Learning

Background:

  • Accurate 3D semantic segmentation is crucial for clinical applications.
  • Voxel-level annotation for 3D medical data is labor-intensive and raises privacy concerns.
  • Current slice-by-slice annotation methods are time-consuming.

Purpose of the Study:

  • To develop a 3D segmentation model that reduces annotation effort.
  • To overcome the limitations of existing weakly supervised methods that require tight bounding boxes.
  • To enable stable model training using relaxed bounding box annotations.

Main Methods:

  • A mixed-supervised training strategy is proposed for 3D segmentation.
  • Only one slice requires full contour annotation; others use relaxed bounding boxes.
  • The method integrates fully supervised learning, relaxed bounding box priors, and contrastive learning.

Main Results:

  • Achieved high segmentation Dice scores: 85.3% on MRI prostate and 83.3% on Vestibular Schwannoma datasets.
  • Outperformed state-of-the-art methods using relaxed bounding box annotations.
  • Demonstrated stable model performance despite variations in bounding box accuracy.

Conclusions:

  • A mixed-supervised learning method for 3D medical imaging is presented.
  • The approach allows for stable segmentation with reduced annotation accuracy requirements.
  • Facilitates easier model training on large-scale medical datasets.