Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of Descemet Stripping Endothelial Keratoplasty in Eyes With Anterior Chamber Intraocular Lenses.

Cornea·2026
Same author

Semaglutide and Neovascular Age-Related Macular Degeneration Among Adults with Type 2 Diabetes: An OHDSI Network Study.

Ophthalmology·2026
Same author

Early Neurodevelopmental Outcomes in Children With Congenital Heart Disease.

JAMA network open·2026
Same author

Mirvetuximab Soravtansine Exposure and Incidence of Cataract Surgery.

JAMA network open·2026
Same author

Ligneous conjunctivitis presenting after strabismus surgery in the eighth decade of life.

American journal of ophthalmology case reports·2026
Same author

PERIVASCULAR MULTIFOCAL CHOROIDITIS WITH PANUVEITIS: Clinical and Multimodal Imaging Features.

Retina (Philadelphia, Pa.)·2026

Related Experiment Video

Updated: Jul 12, 2025

Conjunctival Commensal Isolation and Identification in Mice
07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

4.5K

Pathogen Surveillance for Acute Infectious Conjunctivitis.

Edmund Tsui1,2, Ruti Sella3,4, Vivien Tham5,6

  • 1Ocular Inflammatory Disease Center, UCLA Stein Eye Institute, Los Angeles, California.

JAMA Ophthalmology
|November 2, 2023
PubMed
Summary
This summary is machine-generated.

Microbial causes of acute infectious conjunctivitis vary by geographic location. Purulent discharge is common but not always indicative of bacterial infection, highlighting the need for better diagnostics.

More Related Videos

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
07:35

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

10.4K
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

11.5K

Related Experiment Videos

Last Updated: Jul 12, 2025

Conjunctival Commensal Isolation and Identification in Mice
07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

4.5K
A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
07:35

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

10.4K
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

11.5K

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Acute infectious conjunctivitis is a prevalent public health concern.
  • Understanding regional variations in causative agents is crucial for effective treatment strategies.

Purpose of the Study:

  • To investigate the geographical distribution and microbial causes of acute infectious conjunctivitis.
  • To inform clinical management and antibiotic stewardship.

Main Methods:

  • A cross-sectional study involving 52 patients with presumed acute infectious conjunctivitis across five international sites.
  • Unbiased RNA deep sequencing was employed for pathogen identification.

Main Results:

  • Human adenovirus species D was detected in 25% of cases.
  • Diverse pathogens including coronaviruses, herpes simplex virus, bacteria, and fungi were identified.
  • Purulent discharge was observed in 62% of patients, yet bacterial pathogens were confirmed in only 8%.

Conclusions:

  • Significant regional variations in conjunctivitis pathogens were observed between US and Israeli sites.
  • Purulent discharge has low specificity for bacterial conjunctivitis, suggesting a need for advanced diagnostics.
  • Further research into RNA deep sequencing cost-effectiveness and clinical monitoring is warranted.