Correlation between ischemic stroke topography and female urinary incontinence

Area of Science:

• Neurology
• Urology
• Women's Health

Background:

• Urinary incontinence (UI) is a common complication following ischemic stroke.
• Understanding the specific brain regions affected by stroke is crucial for predicting UI onset.
• Identifying risk factors can aid in targeted prevention and management strategies for post-stroke UI in women.

Purpose of the Study:

• To investigate the association between the location of ischemic stroke lesions and the development of urinary incontinence.
• To identify predictors of post-stroke urinary incontinence in a cohort of women.

Main Methods:

• A prospective follow-up study of women with ischemic stroke confirmed by neuroimaging (CT or MRI).
• Participants underwent clinical evaluation and urodynamic studies at 6 months post-stroke.
• Statistical analyses, including non-parametric tests and logistic regression, were used to compare groups and identify predictors.

Main Results:

• Frontal lobe lesions were significantly more common in women who developed UI (82.9%) compared to continent women (51.2%).
• Higher body mass index (BMI) and a greater number of vaginal deliveries were identified as significant risk factors for post-stroke UI.
• Left parietal lobe lesions were associated with a lower likelihood of UI in continent women.

Conclusions:

• The topography of ischemic stroke, particularly frontal lobe lesions, is correlated with the onset of urinary incontinence.
• Frontal lobe lesions, elevated BMI, and a higher number of vaginal deliveries are significant predictors of post-stroke UI in women.