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Published on: June 21, 2015
Efficacy of copper oxide nanoparticles using Piper longum and Piper betle
Tejitha Ambati1, Vamshi Nizampuram1, Sahana Selvaganesh1
1Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Chennai, Tamilnadu, India.
Abstract:
It is of interest to evaluate the antibacterial, anti-inflammatory, and antioxidant effects of copper nanoparticles synthesized using Piper longum and Piper betle. The copper nanoparticles were characterized using various techniques and found to have a diameter between 30 and 90 nm. The nanoparticles exhibited significant antibacterial activity against E. faecalis, S. aureus, C. albicans, and S. Mutans, comparable to gold standards. They also demonstrated anti-inflammatory effects similar to the gold standard values. Furthermore, the copper nanoparticles displayed antioxidant capabilities, with maximum inhibition of 85.16% at 50 g/ml and a minimum inhibition of 50.62% at 10 g/ml. Overall, the study suggests that Piper longum and Piper betle mediated copper nanoparticles possess promising antibacterial, anti-inflammatory, and antioxidant properties, indicating their potential use in various applications.

