Bile duct carcinoma associated with multiple von Meyenburg complexes in the liver

A 61-year-old white woman was found to have disseminated abdominal carcinoma at autopsy. The primary site proved to be a bile duct carcinoma arising from ductal epithelium of multiple von Meyenburg complexes of the liver. No other neoplastic lesion was found elsewhere after careful, gross, microscopic examination. This case is thought to represent malignant transformation of the hamartomatous growth, previously reported only exceptionally.